This tutorial will show you how to Set a Default Signature in Outlook. Setting up a Default Outlook signature is a standard setting in Outlook but there is more to this feature then you may realize. If you work with multiple Outlook accounts a Default Signature can be set for each Outlook account. This allows you to create a signature personalized for each account. You can also prevent your Default Signature from appearing on email reply and forwards. This makes your email threads that much shorter and easier to navigate through past responses.